Zhi Yu, PhD

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Dr. Zhi Yu is an Investigator, Assistant Professor at the Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, and an Affiliate Faculty member at the Broad Institute of MIT and Harvard. Her research focuses on computational modeling of human multi-omics data to explore the mechanisms underlying cardiovascular and other age-related diseases, aiming to identify personalized strategies for disease prevention and treatment. She has particular expertise in (1) age-related clonal hematopoiesis (clonal expansions in the blood-forming system) and its somatic-germline interactions, and (2) large-scale proteomics. Dr. Yu’s research is supported by the National Human Genome Research Institute (K99/R00), where she develops and applies statistical genetics and machine learning methods to multi-omics data to examine the patterns of clonal hematopoiesis-associated diseases. She is also supported by the Fondation Leducq Clonal Hematopoiesis and Atherosclerosis Network (Early Career Investigator Award).

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